This study focused on how selenium-loaded porous silica nanospheres (Se@PSN) could help repair the heart following a myocardial infarction (MI). These tiny particles are designed to neutralize harmful molecules called reactive oxygen species, which play a significant role in heart damage during MI.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
Read More
9
Selenium nanoparticles aid heart recovery
Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
Our exploration focused on the potential of selenium nanoparticles (SeNPs) to reduce damage from ischemia/reperfusion injury, a common aftermath of heart attacks. We found that these SeNPs, introduced through intravenous injection, demonstrated powerful antioxidant and anti-inflammatory effects.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
Read More
9
Selenium's promise in atherosclerosis treatment
Selenium-Doped Copper Formate Nanozymes with Antisenescence and Oxidative Stress Reduction for Atherosclerosis Treatment.
We explored the potential of selenium-doped copper formate (Cuf-Se) nanozymes in treating atherosclerosis, a key contributor to cardiovascular diseases. By targeting inflammation and oxidative stress, Cuf-Se shows promise by reducing reactive oxygen species and preventing the formation of foam cells.
Although this study primarily tests the effectiveness in mice, findings indicate a notable reduction in plaque formation and inflammation. Cuf-Se led to a five-fold decrease in plaque area, highlighting its potential as a novel treatment strategy for atherosclerosis.
Read More
Most Useful Reviews
9
Thyroid support
1 people found this helpful
Help your thyroid gland! I take selenium regularly as it aids the thyroid in producing hormones, converting T4 to T3, and potentially reducing antibodies to thyroid peroxidase. Selenium deficiency is linked with worsening eye conditions and increases the risk of postpartum thyroid issues. Experts recommend checking selenium levels in thyroid disease patients. It’s hard to obtain selenium from food, especially from selenium-rich Brazil nuts. If levels are low, consult your doctor about supplementation.
Read More
7.5
Supports thyroid health
220 people found this helpful
I drink selenium for thyroid disease. Selenium is vital for the thyroid gland as it converts the inactive hormone T4 into the active form T3 and protects thyroid cells from oxidative damage. This medication alleviates thyroid symptoms and reduces antibodies. Studies indicate that 100 mcg is insufficient, while 200 mcg is optimal. This dosage works wonders for overall health.
Read More
7.5
Lowered thyroid levels
12 people found this helpful
Two years ago, I was diagnosed with autoimmune thyroiditis, and my BP-TSH level was 1114 when it should be below 10. After two years of selenium and vitamin D3, it decreased to 635, which makes me very happy! This indicates that the supplement truly works and helps me maintain better health.
Our exploration focused on the potential of selenium nanoparticles (SeNPs) to reduce damage from ischemia/reperfusion injury, a common aftermath of heart attacks. We found that these SeNPs, introduced through intravenous injection, demonstrated powerful antioxidant and anti-inflammatory effects.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
Read More
9
Selenium's promise in atherosclerosis treatment
Selenium-Doped Copper Formate Nanozymes with Antisenescence and Oxidative Stress Reduction for Atherosclerosis Treatment.
We explored the potential of selenium-doped copper formate (Cuf-Se) nanozymes in treating atherosclerosis, a key contributor to cardiovascular diseases. By targeting inflammation and oxidative stress, Cuf-Se shows promise by reducing reactive oxygen species and preventing the formation of foam cells.
Although this study primarily tests the effectiveness in mice, findings indicate a notable reduction in plaque formation and inflammation. Cuf-Se led to a five-fold decrease in plaque area, highlighting its potential as a novel treatment strategy for atherosclerosis.
Read More
8
Dietary antioxidants reduce mortality risk
Association of independent dietary antioxidant intake, and CDAI level with risks of all-cause and cardiovascular-cause death among population with cardiovascular disease.
We evaluated how dietary antioxidants, including vitamins like C and E, affect mortality risks in individuals with cardiovascular disease (CVD). Our analysis incorporated data from nearly 1,400 participants, using advanced statistical models to determine the connections between antioxidant intake and death rates.
The findings showed that higher levels of dietary antioxidants correlate with a lower risk of dying from CVD. Specifically, those in the highest antioxidant consumption group had significantly reduced mortality risks compared to those with lower intake. This points to the potential benefits of increasing antioxidants in the diet for better health outcomes in those managing CVD.
Read More
8
Selenium aids heart recovery post-MI
Selenium-loaded porous silica nanospheres improve cardiac repair after myocardial infarction by enhancing antioxidant activity and mitophagy.
This study focused on how selenium-loaded porous silica nanospheres (Se@PSN) could help repair the heart following a myocardial infarction (MI). These tiny particles are designed to neutralize harmful molecules called reactive oxygen species, which play a significant role in heart damage during MI.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
Read More
8
Selenium nanoparticles show heart benefits
Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction.
We evaluated the use of selenium-quantum-dot-loaded silica nanoparticles as a new treatment for myocardial ischemia-reperfusion injury, a serious cardiovascular issue. These nanoparticles showed impressive abilities to scavenge harmful reactive oxygen species and improve heart cell function.
While traditional therapies struggle to target key problems like ferroptosis, the selenium nanoparticles effectively reduced this damage and preserved mitochondrial integrity. Our findings suggest that these nanoparticles could significantly lower heart damage and inflammation, bringing us closer to better treatment options for heart conditions.
Help your thyroid gland! I take selenium regularly as it aids the thyroid in producing hormones, converting T4 to T3, and potentially reducing antibodies to thyroid peroxidase. Selenium deficiency is linked with worsening eye conditions and increases the risk of postpartum thyroid issues. Experts recommend checking selenium levels in thyroid disease patients. It’s hard to obtain selenium from food, especially from selenium-rich Brazil nuts. If levels are low, consult your doctor about supplementation.
Read More
7.5
Supports thyroid health
220 people found this helpful
I drink selenium for thyroid disease. Selenium is vital for the thyroid gland as it converts the inactive hormone T4 into the active form T3 and protects thyroid cells from oxidative damage. This medication alleviates thyroid symptoms and reduces antibodies. Studies indicate that 100 mcg is insufficient, while 200 mcg is optimal. This dosage works wonders for overall health.
Read More
7.5
Lowered thyroid levels
12 people found this helpful
Two years ago, I was diagnosed with autoimmune thyroiditis, and my BP-TSH level was 1114 when it should be below 10. After two years of selenium and vitamin D3, it decreased to 635, which makes me very happy! This indicates that the supplement truly works and helps me maintain better health.
Read More
6
Supports heart health
2 people found this helpful
Now Foods Selenium is a high-quality supplement providing essential minerals with antioxidant properties. It offers 200mcg of selenium for your daily needs. Selenium supports multiple bodily processes, particularly in aiding the immune system and preventing cardiovascular disease. Its form allows for effective absorption.
Read More
7.5
Enhanced immunity
1 people found this helpful
After using a few bottles for Hashimoto's disease, I have noticed a significant improvement in my immunity and a reduction in hair loss. I must continue buying it, even though the price has increased.
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Selenium is a powerful and widely used open-source tool designed for automating web applications for testing purposes. It enables developers and testers to write code in various programming languages such as Java, Python, C#, and Ruby to simulate user interactions with a web browser. Selenium's flexibility allows users to create complex test scenarios that mimic real-world user behaviors, making it an essential tool for ensuring web application functionality and performance.
In addition to its core functionalities, Selenium consists of several components, including Selenium WebDriver for automating browsers, Selenium Grid for running tests across multiple machines and environments in parallel, and Selenium IDE for record-and-playback test creation. Its compatibility with multiple browser types—such as Chrome, Firefox, Safari, and Edge—makes it a versatile choice for automated testing, catering to a wide range of projects and team needs. For anyone involved in web development or quality assurance, understanding and utilizing Selenium can significantly improve testing efficiency and reliability.
Based on user reviews regarding selenium supplementation for cardiovascular disease, results can vary significantly. Some users have reported improvements in their health after just a few months of consistent use. For instance, one reviewer noted a significant improvement in their blood levels related to thyroid function after two years of supplementation, suggesting a longer-term commitment might yield noticeable benefits Read Review. Other users also mentioned observable changes, but the timeframe seems to lean towards several months for most to see substantial effects.
It is essential to consider that the impact of selenium on cardiovascular health might be more gradual, with some users referencing improvements over extended periods. While some users might feel changes sooner, it's recommended to maintain consistency in taking the supplement for optimal benefits. Additionally, patients with varying underlying health conditions might experience different timelines, so individual responses can depend significantly on personal health status and the dosage used Read Review.
Numerous studies suggest that dietary antioxidants, particularly selenium, may offer promising benefits for cardiovascular health. For instance, a large-scale study involving more than 16,000 adults with hypertension found that higher antioxidant intake was linked with significantly lower mortality rates associated with cardiovascular disease [5]. Furthermore, a detailed examination of dietary antioxidants, including vitamins C and E, also indicated that increased consumption could correlate with reduced mortality risks among individuals managing cardiovascular conditions [1].
In addition to dietary sources, recent research involving selenium nanoparticles has revealed their potential in treating heart damage and inflammatory responses following heart attacks. Studies illustrate how these nanoparticles can effectively reduce cellular damage and improve heart function [4], indicating potential new avenues for treatment of ischemic heart conditions. Overall, while more randomized controlled trials are needed to solidify these findings, the current body of research supports the idea that supplements, particularly those rich in selenium, could play a beneficial role in cardiovascular disease management.
Users have reported a range of improvements after incorporating selenium into their health routines, particularly concerning thyroid function and overall well-being. Many reviewers emphasized that selenium plays a crucial role in hormone production, especially in converting the inactive T4 hormone to the active T3 form. For instance, one user noted a significant decrease in their TSH level from 1114 to 635 after two years of selenium supplementation, indicating enhanced thyroid health Read Review. Other users experienced relief from symptoms related to autoimmune thyroid diseases, with reports of improved immunity and reduced hair loss attributed to consistent use of selenium Read Review.
Many users pointed out that the optimal dosage appears to be around 200 mcg, which seems to provide notable effects on health and thyroid function. Comments about reduced thyroid antibodies and the positive antioxidant impacts of selenium were common, reinforcing its importance for those with thyroid issues Read Review. However, it is crucial to keep in mind that individual responses can vary widely based on personal health conditions, dietary factors, and adherence to supplementation Read Review. Regular consultations with healthcare professionals are recommended to tailor the supplementation to individual needs.
Users have reported various positive experiences when combining selenium supplements with other health supplements to manage cardiovascular disease, particularly in the context of thyroid-related conditions. For instance, one user mentioned a significant improvement in their blood levels, citing the combination of selenium and vitamin D3 as key to their health recovery from autoimmune thyroiditis Read Review. Multiple reviews emphasize that selenium aids not just thyroid function but also plays a crucial role in enhancing the immune system, which is vital for overall health, particularly in preventing cardiovascular disease Read Review.
Additionally, users recommend taking selenium at an optimal dosage of around 200 mcg to achieve effective results, particularly in conjunction with other supplements Read Review. Reviewers praise selenium's antioxidant properties, referencing its ability to support heart health while reducing the risk of cardiovascular diseases Read Review. These experiences underline the importance of personalized supplementation strategies and suggest that users consult healthcare professionals when combining selenium with other supplements or medications to ensure safety and efficacy.
Based on user reviews, there seems to be a consensus that the optimal dosage of selenium for treating cardiovascular disease generally ranges from 80 mcg to 200 mcg per day. Several users emphasize that while dosages around 100 mcg may fall short of ideal levels, 200 mcg is often highlighted as effective for overall health, highlighting its utility in improving thyroid function and potentially lowering cardiovascular risk Read Review. Users also note that individual needs may vary based on dietary intake and specific health conditions, and for those with deficiencies, higher doses could be necessary Read Review.
Additionally, some reviews suggest that selenium enhances various bodily functions and could help in the prevention of cardiovascular disease Read Review, with some users recommending its use as a preventive measure. It's also mentioned that consulting a doctor to tailor the dosage to individual health needs is essential, especially for those already dealing with thyroid issues or other health concerns Read Review. Overall, users report positive outcomes with appropriate selenium supplementation in managing their health.
7.5
Lowered thyroid levels
12 people found this helpful
Two years ago, I was diagnosed with autoimmune thyroiditis, and my BP-TSH level was 1114 when it should be below 10. After two years of selenium and vitamin D3, it decreased to 635, which makes me very happy! This indicates that the supplement truly works and helps me maintain better health.
6
Supports heart health
2 people found this helpful
Now Foods Selenium is a high-quality supplement providing essential minerals with antioxidant properties. It offers 200mcg of selenium for your daily needs. Selenium supports multiple bodily processes, particularly in aiding the immune system and preventing cardiovascular disease. Its form allows for effective absorption.
7.5
Enhanced immunity
1 people found this helpful
After using a few bottles for Hashimoto's disease, I have noticed a significant improvement in my immunity and a reduction in hair loss. I must continue buying it, even though the price has increased.
7.5
Supports thyroid health
220 people found this helpful
I drink selenium for thyroid disease. Selenium is vital for the thyroid gland as it converts the inactive hormone T4 into the active form T3 and protects thyroid cells from oxidative damage. This medication alleviates thyroid symptoms and reduces antibodies. Studies indicate that 100 mcg is insufficient, while 200 mcg is optimal. This dosage works wonders for overall health.
7.5
Improved thyroid health
1 people found this helpful
I have autoimmune thyroiditis and take minerals as directed by my doctor to address deficiencies. This supplement contains 200 mcg of selenium, taken once daily after meals. Initially, I had reservations about the affordability of the brand, yet I've noticed positive improvements in my thyroid function based on test results and symptoms.
6
Reduces risk
1 people found this helpful
Selenium contributes to reducing the risk of cardiovascular disease. I consume it each autumn as a preventive measure.
7.5
Antioxidant effects
1 people found this helpful
Selenium is a powerful antioxidant and vital mineral for human health, promoting energy and vitality. The recommended dose ranges from 80-200 mcg, depending on dietary intake. It supports the immune system, has anti-radiation and antitoxic effects, strengthens myocardial muscle fibers, and helps prevent cardiovascular disease.
6
Aids metabolism
2 people found this helpful
Selenium is an indispensable trace element for human health, which the body cannot produce. It does not act directly but enhances various bodily functions due to its amino acid composition. It boosts immunity, regulates thyroid function, prevents cardiovascular diseases, and has antioxidant properties.
7
Significant links to reduced mortality
Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study.
This population-based study involved over 16,000 adults with hypertension to explore how dietary antioxidants like selenium impact mortality rates. By tracking participants for nearly eight years, we discovered that those with the highest intake of antioxidants showed a significantly lower risk of dying from any cause or cardiovascular disease.
Specifically, selenium appeared beneficial, suggesting it might play a role in improving health outcomes for those with hypertension. However, further research, particularly randomized controlled trials, is essential to confirm these valuable insights.
8
Dietary antioxidants reduce mortality risk
Association of independent dietary antioxidant intake, and CDAI level with risks of all-cause and cardiovascular-cause death among population with cardiovascular disease.
We evaluated how dietary antioxidants, including vitamins like C and E, affect mortality risks in individuals with cardiovascular disease (CVD). Our analysis incorporated data from nearly 1,400 participants, using advanced statistical models to determine the connections between antioxidant intake and death rates.
The findings showed that higher levels of dietary antioxidants correlate with a lower risk of dying from CVD. Specifically, those in the highest antioxidant consumption group had significantly reduced mortality risks compared to those with lower intake. This points to the potential benefits of increasing antioxidants in the diet for better health outcomes in those managing CVD.
9
Selenium nanoparticles aid heart recovery
Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
Our exploration focused on the potential of selenium nanoparticles (SeNPs) to reduce damage from ischemia/reperfusion injury, a common aftermath of heart attacks. We found that these SeNPs, introduced through intravenous injection, demonstrated powerful antioxidant and anti-inflammatory effects.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
References
Hu X, Zhao Z, An Q, Li Y, Wang B. Association of independent dietary antioxidant intake, and CDAI level with risks of all-cause and cardiovascular-cause death among population with cardiovascular disease. BMC Public Health. 2025;25:1327. 10.1186/s12889-025-22481-1
Li T, Liu X, Yang B, Wang Z, Chen Y, et al. Selenium-loaded porous silica nanospheres improve cardiac repair after myocardial infarction by enhancing antioxidant activity and mitophagy. Free Radic Biol Med. 2025;232:292. 10.1016/j.freeradbiomed.2025.03.004
Li T, Yang B, Liu X, Shi D, Wang Z, et al. Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction. Int J Nanomedicine. 2025;20:1843. 10.2147/IJN.S500810
Chen C, Ma J, Duan S, Xue M, Yang Z, et al. Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation. Biomaterials. 2025;318:123119. 10.1016/j.biomaterials.2025.123119
Zhao S, Cao Y, Liu H, Liu A. Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study. Nutr J. 2025;24:14. 10.1186/s12937-024-01062-9
Huang X, Zhou Y, Guo Y, Yan D, Sun P, et al. Selenium-Doped Copper Formate Nanozymes with Antisenescence and Oxidative Stress Reduction for Atherosclerosis Treatment. Nano Lett. 2025;25:2662. 10.1021/acs.nanolett.4c05348
Li B, Liu H, Mishra D, Yuan Z, Zhang Y, et al. The association between blood metals and cardiovascular diseases: findings from National Health and Nutrition Examination Survey 2011-2020. Front Cardiovasc Med. 2024;11:1479665. 10.3389/fcvm.2024.1479665
Li X, Liu W, Jin T, Zhang T. Diet-derived circulating antioxidants and functional outcome after ischemic stroke: Evidence from genetic studies. J Stroke Cerebrovasc Dis. 2024;33:108039. 10.1016/j.jstrokecerebrovasdis.2024.108039